TKTL2

Across TCGA patient cohorts, TKTL2 protein abundance is significantly associated with the RNA expression of many other genes, with 160 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible TKTL2-associated genes across cancer lineages are FAM83D, CCN4, and GARS1. Each is linked with TKTL2 in more than 1 cancer types. Because this analysis shows association rather than direction, both TKTL2-to-partner and partner-to-TKTL2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TKTL2 versus FAM83D in LUAD, with a Pearson correlation of -0.80.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TKTL2→partner) and Y-score (partner→TKTL2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	FAM83D →	-2.337	-1.019	.001	.004	3	1
LUAD	CCN4 →	-1.697	-1.019	.009	.004	3	1
LUAD	GARS1 →	-0.779	-1.019	.006	.004	3	1
LUAD	SIAE →	+2.097	+1.045	.005	.003	3	1
LUAD	AICDA →	-0.239	-1.155	<.001	.006	3	1
LUAD	PTGIS →	-1.540	-1.004	.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 160 associations by consensus.

TKTL2 vs FAM83D — LUAD

Explore this scatter interactively →