TKTL2

Across TCGA patient cohorts, TKTL2 protein abundance is significantly associated with the protein abundance of many other proteins, with 288 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible TKTL2-associated proteins across cancer lineages are DGKQ_S376, PATJ_T335, and PTAR1. Each is linked with TKTL2 in more than 1 cancer types. Because this analysis shows association rather than direction, both TKTL2-to-partner and partner-to-TKTL2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TKTL2 versus DGKQ_S376 in LUAD, with a Pearson correlation of 0.67.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TKTL2→partner) and Y-score (partner→TKTL2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	DGKQ_S376 →	+0.772	+1.099	.001	.002	3	1
LUAD	PATJ_T335 →	+0.646	+0.778	<.001	.006	2	1
LUAD	PTAR1 →	+0.660	+1.286	.004	.006	2	1
LUAD	PTGIS →	-0.977	-1.005	.001	.004	2	1
LUAD	PTPRG →	+0.867	+1.070	.005	.001	2	1
LUAD	TNKS1BP1_S691 →	+0.679	+1.050	.002	.003	2	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 288 associations by consensus.

TKTL2 vs DGKQ_S376 — LUAD

Explore this scatter interactively →