TKTL2

Across TCGA cell cohorts, TKTL2 RNA expression is significantly associated with the RNA expression of many other genes, with 2,454 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible TKTL2-associated genes across cancer lineages are MARCHF1, XKR6, and PLAC8L1. Each is linked with TKTL2 in more than 3 cancer types. Because this analysis shows association rather than direction, both TKTL2-to-partner and partner-to-TKTL2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TKTL2 versus MARCHF1 in BONE, with a Pearson correlation of 0.57.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TKTL2→partner) and Y-score (partner→TKTL2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	MARCHF1 →	+1.382	+0.023	.001	.003	3	4
CNS	XKR6 →	+0.937	+0.020	<.001	<.001	3	3
STOMACH	PLAC8L1 →	+0.402	+0.011	<.001	.008	3	2
BLOOD_Leukemia	OOSP4A →	+0.395	+0.030	<.001	<.001	3	2
LUNG_SCLC	OR52N1 →	+0.081	+0.176	.002	.001	3	2
LUNG_NSCLC_LUSC	OR2AE1 →	+0.123	+0.036	<.001	.004	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,454 associations by consensus.

TKTL2 vs MARCHF1 — BONE

Explore this scatter interactively →