TKTL1

Across TCGA cell cohorts, TKTL1 RNA expression is significantly associated with the go_rna of many other GO terms, with 735 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible TKTL1-associated GO terms across cancer lineages are Biological process involved in interaction with symbiont, Kidney epithelium development, and Negative regulation of myoblast fusion. Each is linked with TKTL1 in more than 3 cancer types. Because this analysis shows association rather than direction, both TKTL1-to-partner and partner-to-TKTL1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Biological process involved in interaction with symbiont grouped by TKTL1-low versus TKTL1-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TKTL1→partner) and Y-score (partner→TKTL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Biological process involved in interaction with symbiont →	+0.119	+0.078	.004	.001	3	3
SKIN	Kidney epithelium development →	-0.082	-0.977	<.001	.005	3	3
PANCREAS	Negative regulation of myoblast fusion →	+0.074	+0.031	.002	.001	3	3
PANCREAS	Regulation of protein localization to mitochondrion →	+0.073	+0.036	.001	.002	3	3
UPPER_AERODIGESTIVE_TRACT	Negative regulation of cAMP/PKA signal transduction →	-0.075	-0.069	.002	.005	3	3
BREAST	Energy derivation by oxidation of organic compounds →	+0.040	+0.075	<.001	.003	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 735 associations by consensus.

Biological process involved in interaction with symbiont by TKTL1 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →