TJP3

Across TCGA patient cohorts, TJP3 protein abundance is significantly associated with the RNA expression of many other genes, with 14,357 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible TJP3-associated genes across cancer lineages are C9orf152, SMIM22, and BCAS1. Each is linked with TJP3 in more than 6 cancer types. Because this analysis shows association rather than direction, both TJP3-to-partner and partner-to-TJP3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TJP3 versus C9orf152 in BRCA, with a Pearson correlation of 0.41.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TJP3→partner) and Y-score (partner→TJP3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	C9orf152 →	+1.869	+0.566	<.001	<.001	3	7
BRCA	SMIM22 →	+1.734	+0.624	<.001	<.001	3	7
LUAD	BCAS1 →	+1.819	+0.453	<.001	<.001	3	7
LSCC	TMC5 →	+1.913	+0.666	<.001	<.001	3	6
BRCA	MLPH →	+1.795	+0.345	<.001	<.001	3	6
UCEC	TSPAN1 →	+1.730	+0.412	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,357 associations by consensus.

TJP3 vs C9orf152 — BRCA

Explore this scatter interactively →