TJP1

Across TCGA cell cohorts, TJP1 RNA expression is significantly associated with the RNA expression of many other genes, with 10,693 significant associations in total. BONE shows the largest number of these associations.

The most reproducible TJP1-associated genes across cancer lineages are LRRC57, UBE3A, and INO80. Each is linked with TJP1 in more than 11 cancer types. Because this analysis shows association rather than direction, both TJP1-to-partner and partner-to-TJP1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TJP1 versus LRRC57 in UPPER_AERODIGESTIVE_TRACT, with a Pearson correlation of 0.59.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TJP1→partner) and Y-score (partner→TJP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	LRRC57 →	+0.880	+0.950	<.001	<.001	3	12
KIDNEY	UBE3A →	+0.815	+1.237	<.001	<.001	3	11
OESOPHAGUS	INO80 →	+1.093	+1.312	<.001	.002	2	11
PANCREAS	TMOD3 →	+1.359	+1.080	<.001	<.001	3	10
BONE	PICALM →	+1.036	+2.349	<.001	<.001	3	10
SOFT_TISSUE	ZNF106 →	+1.230	+0.606	<.001	.002	2	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,693 associations by consensus.

TJP1 vs LRRC57 — UPPER_AERODIGESTIVE_TRACT

Explore this scatter interactively →