TJAP1

Across TCGA pan-cancer cohorts, TJAP1 mass-spec protein is linked to patient survival in 9 of 34 cancer types, making it a survival-associated TJAP1 data layer compared with 25 for mass-spec protein and 3 for mutation status.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher TJAP1 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated TJAP1 expression acts as an unfavorable survival marker, although some lineages such as LUAD and CCRCC show a favorable association.

HNSC, LUAD, and PDAC are the cancer types where TJAP1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	DFS	Median	III,IV	0.303	0.886	.007	29	view →
LUAD	OS	Median	III,IV	0.819	0.337	.005	15	view →
PDAC	DFS	Median	III,IV	0.376	0.936	.004	13	view →
COAD	DFS	Median	III,IV	0.800	1.000	.016	12	view →
GBM	DFS	Median	All	0.645	0.784	.003	6	view →
CCRCC	OS	Median	IV	1.000	0.202	.034	5	view →
OV	DFS	Median	All	0.869	1.000	.044	4	view →
UCEC	OS	Tertile	II,III,IV	0.678	1.000	.048	4	view →
LSCC	DFS	Quartile	II,III,IV	1.000	0.353	.024	3	view →

Pink = unfavorable, green = favorable. Showing the 9 strongest of 9 lineages.

TJAP1–HNSC (DFS)

Open the HNSC breakdown →