TJAP1

Across TCGA cell cohorts, TJAP1 mutation is significantly associated with the RNA expression of many other genes, with 15 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible TJAP1-associated genes across cancer lineages are XAGE5, SEL1L2, and TLE7. Each is linked with TJAP1 in more than 1 cancer types. Because this analysis shows association rather than direction, both TJAP1-to-partner and partner-to-TJAP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, XAGE5 grouped by TJAP1-low versus TJAP1-high in OVARY.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TJAP1→partner) and Y-score (partner→TJAP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	XAGE5 →	+0.255	+5.196	<.001	.005	3	1
BLOOD_Lymphoma	SEL1L2 →	+0.011	+4.643	.004	.005	3	1
BLOOD_Lymphoma	TLE7 →	+0.012	+4.643	<.001	.005	3	1
LARGE_INTESTINE	BBS7 →	+0.705	+3.064	.001	.009	3	1
LARGE_INTESTINE	PRMT9 →	+0.644	+3.192	<.001	.007	3	1
LARGE_INTESTINE	MIS12 →	+0.770	+3.082	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 15 associations by consensus.

XAGE5 by TJAP1 expression — OVARY

Explore this box plot interactively →