Across TCGA pan-cancer cohorts, TIPINP1 RNA differs between tumor and matched normal tissue in 3 of 18 cancer types tested, making tumor–normal expression one of TIPINP1’s most consistent transcriptional readouts.
The strongest signal is observed in breast invasive carcinoma (BRCA), where TIPINP1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types TIPINP1 is over-expressed in tumor, although a few such as LUSC show the opposite, repressed pattern.
BRCA, LUSC, and KICH are the cancer types where TIPINP1 tumor–normal differential expression is most reproducible.