TIPARP

Across TCGA cell cohorts, TIPARP RNA expression is significantly associated with the go_rna of many other GO terms, with 4,252 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible TIPARP-associated GO terms across cancer lineages are Response to 2,3,7,8-tetrachlorodibenzodioxine, Positive regulation of smooth muscle cell migration, and Regulation of protein monoubiquitination. Each is linked with TIPARP in more than 9 cancer types. Because this analysis shows association rather than direction, both TIPARP-to-partner and partner-to-TIPARP results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Response to 2,3,7,8-tetrachlorodibenzodioxine grouped by TIPARP-low versus TIPARP-high in BLOOD_Myeloma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TIPARP→partner) and Y-score (partner→TIPARP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Myeloma	Response to 2,3,7,8-tetrachlorodibenzodioxine →	+1.257	+1.451	<.001	<.001	3	10
SKIN	Positive regulation of smooth muscle cell migration →	+0.147	+1.303	<.001	<.001	3	10
LIVER	Regulation of protein monoubiquitination →	+0.163	+1.480	<.001	<.001	2	10
LIVER	Positive regulation of protein monoubiquitination →	+0.163	+1.480	<.001	<.001	2	10
OESOPHAGUS	Regulation of proteolysis →	+0.098	+0.884	<.001	<.001	3	9
STOMACH	Establishment of skin barrier →	+0.157	+1.002	.002	.002	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,252 associations by consensus.

Response to 2,3,7,8-tetrachlorodibenzodioxine by TIPARP expression — BLOOD_Myeloma

Explore this box plot interactively →