TIPARP-AS1

Across TCGA pan-cancer cohorts, TIPARP-AS1 RNA is linked to patient survival in 26 of 34 cancer types, making it the most broadly survival-associated TIPARP-AS1 data layer.

The strongest signal is observed in uveal melanoma (UVM), where higher TIPARP-AS1 RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated TIPARP-AS1 expression acts as an unfavorable survival marker, although some lineages such as UVM and BRCA show a favorable association.

UVM, BRCA, and CESC are the cancer types where TIPARP-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UVM	DFS	Median	All	0.751	0.434	<.001	84	view →
BRCA	OS	Median	All	0.636	0.520	<.001	72	view →
CESC	OS	Quartile	III,IV	0.887	0.314	.002	32	view →
LUSC	OS	Quartile	All	0.829	0.687	.005	30	view →
MESO	OS	Tertile	All	0.593	0.388	.020	22	view →
THYM	DFS	Median	All	0.672	0.938	.023	21	view →
COAD	DFS	Quartile	All	0.769	0.849	.025	19	view →
SKCM	DFS	Median	III,IV	0.360	0.156	.011	19	view →
PAAD	OS	Quartile	All	0.216	0.502	.009	18	view →
CHOL	DFS	Tertile	All	0.138	1.000	.011	16	view →
THCA	DFS	Median	All	0.880	0.775	.008	15	view →
READ	DFS	Tertile	III,IV	0.902	0.523	.007	14	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 26 lineages.

TIPARP-AS1–UVM (DFS)

Open the UVM breakdown →