TINF2

Across TCGA cell cohorts, TINF2 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,985 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible TINF2-associated GO terms across cancer lineages are Protein linear polyubiquitination, Vesicle-mediated transport to the plasma membrane, and Autophagosome organization. Each is linked with TINF2 in more than 12 cancer types. Because this analysis shows association rather than direction, both TINF2-to-partner and partner-to-TINF2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein linear polyubiquitination grouped by TINF2-low versus TINF2-high in PANCREAS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TINF2→partner) and Y-score (partner→TINF2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	Protein linear polyubiquitination →	+0.150	+0.658	<.001	<.001	3	13
KIDNEY	Vesicle-mediated transport to the plasma membrane →	+0.052	+0.682	.001	.002	3	9
PANCREAS	Autophagosome organization →	+0.049	+0.519	.007	.006	2	10
PANCREAS	Amino acid metabolic process →	-0.058	-0.538	.002	.001	3	9
KIDNEY	Golgi vesicle transport →	+0.045	+0.823	.003	.002	3	8
OVARY	Vacuole organization →	+0.046	+0.657	.001	.001	2	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,985 associations by consensus.

Protein linear polyubiquitination by TINF2 expression — PANCREAS

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