TINAGL1

Across TCGA cell cohorts, TINAGL1 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,212 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible TINAGL1-associated GO terms across cancer lineages are Negative regulation of cell adhesion, Epidermal growth factor receptor signaling pathway, and Rho protein signal transduction. Each is linked with TINAGL1 in more than 13 cancer types. Because this analysis shows association rather than direction, both TINAGL1-to-partner and partner-to-TINAGL1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of cell adhesion grouped by TINAGL1-low versus TINAGL1-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TINAGL1→partner) and Y-score (partner→TINAGL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Negative regulation of cell adhesion →	+0.094	+3.248	<.001	<.001	3	14
OESOPHAGUS	Epidermal growth factor receptor signaling pathway →	+0.112	+2.821	<.001	.001	3	13
OESOPHAGUS	Rho protein signal transduction →	+0.173	+3.829	<.001	<.001	3	13
BREAST	Blood coagulation, extrinsic pathway →	+1.313	+3.680	<.001	<.001	3	13
OESOPHAGUS	Negative regulation of actin filament polymerization →	+0.157	+2.547	<.001	.002	3	13
BONE	Plasma membrane organization →	+0.180	+2.220	<.001	.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,212 associations by consensus.

Negative regulation of cell adhesion by TINAGL1 expression — BREAST

Explore this box plot interactively →