TINAGL1

Across TCGA cell cohorts, TINAGL1 mutation is significantly associated with the RNA expression of many other genes, with 9 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible TINAGL1-associated genes across cancer lineages are OR2A5, FMO1, and MAGEB4. Each is linked with TINAGL1 in more than 1 cancer types. Because this analysis shows association rather than direction, both TINAGL1-to-partner and partner-to-TINAGL1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR2A5 grouped by TINAGL1-low versus TINAGL1-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TINAGL1→partner) and Y-score (partner→TINAGL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	OR2A5 →	+0.032	+4.922	<.001	.009	3	1
LARGE_INTESTINE	FMO1 →	+0.101	+2.921	<.001	.005	3	1
LARGE_INTESTINE	MAGEB4 →	+0.012	+3.678	<.001	.001	3	1
LARGE_INTESTINE	CCDC70 →	+0.036	+2.921	<.001	.005	3	1
LARGE_INTESTINE	CRISP1 →	+0.012	+3.678	<.001	.001	3	1
LARGE_INTESTINE	CDCP2 →	+0.028	+3.141	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 9 associations by consensus.

OR2A5 by TINAGL1 expression — BLOOD_Leukemia

Explore this box plot interactively →