TINAG-AS1

Across TCGA pan-cancer cohorts, TINAG-AS1 RNA is linked to patient survival in 7 of 34 cancer types, making it the most broadly survival-associated TINAG-AS1 data layer.

The strongest signal is observed in lung squamous cell carcinoma (LUSC), where higher TINAG-AS1 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated TINAG-AS1 expression acts as an unfavorable survival marker, although some lineages such as KIRC and STAD show a favorable association.

LUSC, KIRP, and KIRC are the cancer types where TINAG-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUSC	OS	Tertile	All	0.047	0.762	<.001	108	view →
KIRP	OS	Tertile	All	0.555	0.782	<.001	81	view →
KIRC	DFS	Median	III,IV	0.832	0.684	.004	50	view →
UCEC	DFS	Tertile	All	0.115	0.653	<.001	36	view →
PCPG	OS	Tertile	All	0.273	0.971	.001	36	view →
STAD	OS	Tertile	II,III,IV	0.653	0.322	.022	24	view →
THCA	DFS	Tertile	All	0.205	0.814	.035	18	view →

Pink = unfavorable, green = favorable. Showing the 7 strongest of 7 lineages.

TINAG-AS1–LUSC (OS)

Open the LUSC breakdown →