TIMP4

Across TCGA patient cohorts, TIMP4 RNA expression is significantly associated with the protein abundance of many other proteins, with 12,783 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible TIMP4-associated proteins across cancer lineages are MAP1A, RNF213, and SEPTIN11. Each is linked with TIMP4 in more than 4 cancer types. Because this analysis shows association rather than direction, both TIMP4-to-partner and partner-to-TIMP4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TIMP4 versus MAP1A in HNSC, with a Pearson correlation of 0.35.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TIMP4→partner) and Y-score (partner→TIMP4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	MAP1A →	+0.556	+0.820	<.001	<.001	3	5
BRCA	RNF213 →	-0.453	-1.668	<.001	<.001	3	5
PDAC	SEPTIN11 →	+0.379	+0.653	<.001	<.001	3	5
OV	SEPTIN4 →	+0.720	+1.386	<.001	<.001	3	5
OV	CAVIN1_S175 →	+1.496	+2.085	<.001	<.001	3	5
BRCA	CAVIN3 →	+0.594	+1.265	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,783 associations by consensus.

TIMP4 vs MAP1A — HNSC

Explore this scatter interactively →