TIMM8BP1

Across TCGA pan-cancer cohorts, TIMM8BP1 RNA is linked to patient survival in 13 of 34 cancer types, making it the most broadly survival-associated TIMM8BP1 data layer.

The strongest signal is observed in bladder urothelial carcinoma (BLCA), where higher TIMM8BP1 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated TIMM8BP1 expression acts as an unfavorable survival marker, although some lineages such as SKCM show a favorable association.

BLCA, KIRC, and UCEC are the cancer types where TIMM8BP1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
BLCA	DFS	Tertile	All	0.174	0.522	.005	72	view →
KIRC	DFS	Tertile	II,III,IV	0.167	0.760	<.001	72	view →
UCEC	DFS	Tertile	II,III,IV	0.421	0.751	<.001	72	view →
CESC	DFS	Tertile	II,III,IV	0.203	0.716	<.001	54	view →
THCA	DFS	Tertile	IV	0.144	0.884	<.001	36	view →
LUAD	DFS	Tertile	IV	0.342	0.893	<.001	36	view →
UVM	DFS	Tertile	All	0.079	0.746	<.001	27	view →
LGG	OS	Tertile	All	0.196	0.469	.008	27	view →
THYM	OS	Tertile	All	0.549	0.974	.001	27	view →
LUSC	DFS	Tertile	II,III,IV	0.243	0.714	<.001	27	view →
STAD	DFS	Tertile	II,III,IV	0.504	0.662	.017	21	view →
ESCA	DFS	Tertile	II,III,IV	0.130	0.777	.024	18	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 13 lineages.

TIMM8BP1–BLCA (DFS)

Open the BLCA breakdown →