TIMM29

Across TCGA pan-cancer cohorts, TIMM29 mass-spec protein is linked to patient survival in 7 of 34 cancer types, making it a survival-associated TIMM29 data layer compared with 25 for mass-spec protein and 1 for mutation status.

The strongest signal is observed in pancreatic ductal adenocarcinoma (PDAC), where higher TIMM29 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated TIMM29 expression acts as an unfavorable survival marker, although some lineages such as PDAC and LUAD show a favorable association.

PDAC, CCRCC, and LSCC are the cancer types where TIMM29 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
PDAC	DFS	Median	All	0.512	0.303	<.001	29	view →
CCRCC	OS	Quartile	All	0.793	1.000	.023	6	view →
LSCC	OS	Median	III,IV	0.418	0.807	.024	4	view →
HNSC	DFS	Median	IV	0.328	0.889	.014	4	view →
UCEC	DFS	Median	II,III,IV	0.549	0.867	.046	4	view →
LUAD	OS	Median	All	0.910	0.755	.022	3	view →
GBM	OS	Tertile	All	0.232	0.592	.007	2	view →

Pink = unfavorable, green = favorable. Showing the 7 strongest of 7 lineages.

TIMM29–PDAC (DFS)

Open the PDAC breakdown →