TIMM29

Across TCGA cell cohorts, TIMM29 protein abundance is significantly associated with the RNA expression of many other genes, with 2,603 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible TIMM29-associated genes across cancer lineages are KLK10, ESPN, and GPC2. Each is linked with TIMM29 in more than 3 cancer types. Because this analysis shows association rather than direction, both TIMM29-to-partner and partner-to-TIMM29 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TIMM29 versus KLK10 in URINARY_TRACT, with a Pearson correlation of 0.98.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TIMM29→partner) and Y-score (partner→TIMM29) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	KLK10 →	+2.048	+2.555	.001	.004	2	4
LARGE_INTESTINE	ESPN →	+2.389	+1.648	<.001	.003	3	3
BREAST	GPC2 →	+1.516	+2.203	.004	.006	3	2
URINARY_TRACT	SLC35A3 →	+0.589	+2.555	<.001	.004	2	3
SKIN	PMS2 →	+0.805	+1.318	.004	.005	3	2
URINARY_TRACT	BDKRB2 →	+3.046	+2.555	<.001	.004	2	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,603 associations by consensus.

TIMM29 vs KLK10 — URINARY_TRACT

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