TIMM23B-AGAP6

Across TCGA pan-cancer cohorts, TIMM23B-AGAP6 RNA is linked to patient survival in 24 of 34 cancer types, making it the most broadly survival-associated TIMM23B-AGAP6 data layer.

The strongest signal is observed in adrenocortical carcinoma (ACC), where higher TIMM23B-AGAP6 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated TIMM23B-AGAP6 expression acts as an unfavorable survival marker, although some lineages such as BRCA and STAD show a favorable association.

ACC, COAD, and UVM are the cancer types where TIMM23B-AGAP6 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
ACC	OS	Tertile	All	0.278	0.788	<.001	79	view →
COAD	OS	Quartile	All	0.637	0.844	.002	60	view →
UVM	DFS	Median	All	0.334	0.761	.001	55	view →
CESC	OS	Quartile	All	0.840	0.950	.004	50	view →
KIRC	DFS	Median	III,IV	0.551	0.724	.006	47	view →
KICH	DFS	Tertile	III,IV	0.252	1.000	.002	21	view →
BRCA	DFS	Median	III,IV	0.590	0.378	.009	18	view →
MESO	DFS	Quartile	All	0.302	0.490	.018	18	view →
STAD	OS	Median	III,IV	0.683	0.311	.005	12	view →
LUAD	DFS	Median	IV	0.306	0.764	.010	11	view →
SARC	OS	Median	All	0.435	0.761	.001	11	view →
READ	OS	Median	All	0.932	0.446	.028	8	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 24 lineages.

TIMM23B-AGAP6–ACC (OS)

Open the ACC breakdown →