TIMM23

Across TCGA patient cohorts, TIMM23 protein abundance is significantly associated with the RNA expression of many other genes, with 15,735 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible TIMM23-associated genes across cancer lineages are ABCA8, HSPA12B, and RCAN2. Each is linked with TIMM23 in more than 6 cancer types. Because this analysis shows association rather than direction, both TIMM23-to-partner and partner-to-TIMM23 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TIMM23 versus ABCA8 in LSCC, with a Pearson correlation of -0.41.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TIMM23→partner) and Y-score (partner→TIMM23) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	ABCA8 →	-1.091	-0.525	<.001	<.001	3	7
BRCA	HSPA12B →	-0.932	-0.527	<.001	<.001	3	7
LUAD	RCAN2 →	-0.855	-0.389	<.001	<.001	3	7
HNSC	GIMAP6 →	-0.932	-0.278	<.001	<.001	3	6
BRCA	IQGAP2 →	-1.104	-0.426	.001	<.001	3	6
OV	ZEB2 →	-0.854	-0.328	<.001	.002	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,735 associations by consensus.

TIMM23 vs ABCA8 — LSCC

Explore this scatter interactively →