TIMM23

Across TCGA cell cohorts, TIMM23 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,024 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible TIMM23-associated GO terms across cancer lineages are DNA replication initiation, Positive regulation of mitochondrial ATP synthesis coupled electron transport, and DNA replication, removal of RNA primer. Each is linked with TIMM23 in more than 14 cancer types. Because this analysis shows association rather than direction, both TIMM23-to-partner and partner-to-TIMM23 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DNA replication initiation grouped by TIMM23-low versus TIMM23-high in BLOOD_Myeloma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TIMM23→partner) and Y-score (partner→TIMM23) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Myeloma	DNA replication initiation →	+0.167	+1.088	<.001	.003	3	15
PANCREAS	Positive regulation of mitochondrial ATP synthesis coupled electron transport →	+0.131	+0.832	<.001	<.001	3	14
OESOPHAGUS	DNA replication, removal of RNA primer →	+0.116	+0.862	.001	<.001	3	14
URINARY_TRACT	Lagging strand elongation →	+0.177	+0.976	<.001	<.001	3	14
UPPER_AERODIGESTIVE_TRACT	3'-UTR-mediated mRNA destabilization →	-0.144	-0.809	<.001	.003	3	14
PANCREAS	Regulation of mitochondrial ATP synthesis coupled electron transport →	+0.160	+0.835	<.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,024 associations by consensus.

DNA replication initiation by TIMM23 expression — BLOOD_Myeloma

Explore this box plot interactively →