TIMM22

Across TCGA cell cohorts, TIMM22 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,357 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible TIMM22-associated GO terms across cancer lineages are Ribosomal large subunit assembly, Positive regulation of mitotic cell cycle, and Ribosome biogenesis. Each is linked with TIMM22 in more than 14 cancer types. Because this analysis shows association rather than direction, both TIMM22-to-partner and partner-to-TIMM22 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Ribosomal large subunit assembly grouped by TIMM22-low versus TIMM22-high in BLOOD_Myeloma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TIMM22→partner) and Y-score (partner→TIMM22) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Myeloma	Ribosomal large subunit assembly →	+0.138	+0.998	<.001	<.001	3	15
BREAST	Positive regulation of mitotic cell cycle →	+0.086	+0.626	.002	.003	3	15
UPPER_AERODIGESTIVE_TRACT	Ribosome biogenesis →	+0.097	+0.752	.002	.004	3	14
OESOPHAGUS	rRNA processing →	+0.119	+1.097	.005	.001	3	14
UPPER_AERODIGESTIVE_TRACT	Transcription initiation at RNA polymerase II promoter →	+0.085	+0.812	<.001	<.001	3	14
OESOPHAGUS	rRNA metabolic process →	+0.111	+1.097	.007	.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,357 associations by consensus.

Ribosomal large subunit assembly by TIMM22 expression — BLOOD_Myeloma

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