TIMM21

Across TCGA patient cohorts, TIMM21 protein abundance is significantly associated with the RNA expression of many other genes, with 16,460 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible TIMM21-associated genes across cancer lineages are ATP5F1A, TXNL4A, and NARS1. Each is linked with TIMM21 in more than 7 cancer types. Because this analysis shows association rather than direction, both TIMM21-to-partner and partner-to-TIMM21 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TIMM21 versus ATP5F1A in HNSC, with a Pearson correlation of 0.30.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TIMM21→partner) and Y-score (partner→TIMM21) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	ATP5F1A →	+0.728	+0.312	<.001	<.001	3	8
OV	TXNL4A →	+0.533	+0.272	.001	.003	3	7
HNSC	NARS1 →	+0.575	+0.275	<.001	<.001	3	6
GBM	ITGBL1 →	-0.936	-0.425	<.001	<.001	3	5
OV	RBFA →	+0.449	+0.269	.001	.006	3	5
UCEC	GYPC →	-0.848	-0.395	<.001	.002	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,460 associations by consensus.

TIMM21 vs ATP5F1A — HNSC

Explore this scatter interactively →