TIMM21

Across TCGA cell cohorts, TIMM21 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,595 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible TIMM21-associated GO terms across cancer lineages are DNA damage tolerance, Centriole replication, and DNA replication initiation. Each is linked with TIMM21 in more than 13 cancer types. Because this analysis shows association rather than direction, both TIMM21-to-partner and partner-to-TIMM21 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DNA damage tolerance grouped by TIMM21-low versus TIMM21-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TIMM21→partner) and Y-score (partner→TIMM21) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	DNA damage tolerance →	+0.088	+0.893	.006	.001	3	14
BREAST	Centriole replication →	+0.095	+0.961	<.001	<.001	3	14
BLOOD_Myeloma	DNA replication initiation →	+0.182	+1.259	<.001	<.001	3	13
PANCREAS	DNA replication checkpoint signaling →	+0.161	+1.011	<.001	<.001	3	13
OESOPHAGUS	DNA synthesis involved in DNA replication →	+0.092	+0.804	.002	.004	3	13
PANCREAS	Centriole assembly →	+0.080	+1.189	<.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,595 associations by consensus.

DNA damage tolerance by TIMM21 expression — OESOPHAGUS

Explore this box plot interactively →