TIMM13

Across TCGA cell cohorts, TIMM13 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,223 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible TIMM13-associated GO terms across cancer lineages are Cytoplasm protein quality control by the ubiquitin-proteasome system, Pseudouridine synthesis, and Energy coupled proton transmembrane transport, against electrochemical gradient. Each is linked with TIMM13 in more than 14 cancer types. Because this analysis shows association rather than direction, both TIMM13-to-partner and partner-to-TIMM13 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cytoplasm protein quality control by the ubiquitin-proteasome system grouped by TIMM13-low versus TIMM13-high in SKIN.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TIMM13→partner) and Y-score (partner→TIMM13) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	Cytoplasm protein quality control by the ubiquitin-proteasome system →	+0.138	+0.954	<.001	<.001	3	14
OESOPHAGUS	Pseudouridine synthesis →	+0.086	+1.066	.006	.007	2	15
PANCREAS	Energy coupled proton transmembrane transport, against electrochemical gradient →	+0.083	+0.837	<.001	<.001	3	13
PANCREAS	Electron transport coupled proton transport →	+0.083	+0.837	<.001	<.001	3	13
BONE	Enzyme-directed rRNA pseudouridine synthesis →	+0.134	+1.157	<.001	<.001	3	13
BONE	Cytoplasm protein quality control →	+0.169	+1.420	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,223 associations by consensus.

Cytoplasm protein quality control by the ubiquitin-proteasome system by TIMM13 expression — SKIN

Explore this box plot interactively →