TIMD4

Across TCGA patient cohorts, TIMD4 protein abundance is significantly associated with the RNA expression of many other genes, with 345 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible TIMD4-associated genes across cancer lineages are NDRG1, NUCB1, and MED25. Each is linked with TIMD4 in more than 1 cancer types. Because this analysis shows association rather than direction, both TIMD4-to-partner and partner-to-TIMD4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TIMD4 versus NDRG1 in CCRCC, with a Pearson correlation of -0.33.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TIMD4→partner) and Y-score (partner→TIMD4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	NDRG1 →	-0.424	-0.387	.008	.002	3	1
CCRCC	NUCB1 →	-0.243	-0.381	.005	<.001	3	1
CCRCC	MED25 →	-0.234	-0.355	.002	.002	3	1
CCRCC	VRK3 →	-0.202	-0.285	.002	.002	3	1
CCRCC	KDELR1 →	-0.332	-0.467	<.001	<.001	3	1
CCRCC	LIG1 →	-0.333	-0.325	.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 345 associations by consensus.

TIMD4 vs NDRG1 — CCRCC

Explore this scatter interactively →