TIMD4

Across TCGA cell cohorts, TIMD4 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,090 significant associations in total. KIDNEY shows the largest number of these associations.

The most reproducible TIMD4-associated GO terms across cancer lineages are T-helper cell lineage commitment, Alpha-beta T cell lineage commitment, and Positive regulation of protein exit from endoplasmic reticulum. Each is linked with TIMD4 in more than 4 cancer types. Because this analysis shows association rather than direction, both TIMD4-to-partner and partner-to-TIMD4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, T-helper cell lineage commitment grouped by TIMD4-low versus TIMD4-high in BLOOD_Lymphoma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TIMD4→partner) and Y-score (partner→TIMD4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	T-helper cell lineage commitment →	+0.091	+0.499	.001	.007	3	4
BLOOD_Lymphoma	Alpha-beta T cell lineage commitment →	+0.134	+0.588	<.001	.004	3	4
BLOOD_Lymphoma	Positive regulation of protein exit from endoplasmic reticulum →	+0.085	+0.990	<.001	.002	3	4
BLOOD_Lymphoma	T-helper 17 cell lineage commitment →	+0.120	+0.560	.001	.002	3	4
KIDNEY	Regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains →	+0.071	+1.648	.003	.005	3	4
KIDNEY	Demethylation →	-0.088	-1.589	.004	.002	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,090 associations by consensus.

T-helper cell lineage commitment by TIMD4 expression — BLOOD_Lymphoma

Explore this box plot interactively →