TIGD7

Across TCGA patient cohorts, TIGD7 mutation is significantly associated with the RNA expression of many other genes, with 3,826 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TIGD7-associated genes across cancer lineages are ANAPC15P2, TXNL1, and SNORD113-8. Each is linked with TIGD7 in more than 1 cancer types. Because this analysis shows association rather than direction, both TIGD7-to-partner and partner-to-TIGD7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ANAPC15P2 grouped by TIGD7-low versus TIGD7-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TIGD7→partner) and Y-score (partner→TIGD7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	ANAPC15P2 →	+0.108	+5.103	<.001	.008	3	2
COAD	TXNL1 →	+0.446	+3.375	.006	.005	3	2
STAD	SNORD113-8 →	+0.388	+5.463	<.001	.005	3	2
UCEC	SLC7A11 →	+0.889	+1.893	<.001	<.001	3	2
UCEC	CENPU →	+0.759	+2.202	<.001	<.001	3	2
UCEC	BAG3 →	+0.530	+2.386	<.001	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,826 associations by consensus.

ANAPC15P2 by TIGD7 expression — CESC

Explore this box plot interactively →