TIGD6

Across TCGA cell cohorts, TIGD6 mutation is significantly associated with the RNA expression of many other genes, with 11 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible TIGD6-associated genes across cancer lineages are TAAR8, KRTAP10-5, and OOSP4B. Each is linked with TIGD6 in more than 1 cancer types. Because this analysis shows association rather than direction, both TIGD6-to-partner and partner-to-TIGD6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TAAR8 grouped by TIGD6-low versus TIGD6-high in LUNG_NSCLC_LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TIGD6→partner) and Y-score (partner→TIGD6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	TAAR8 →	+0.017	+4.662	<.001	.005	3	1
LUNG_NSCLC_LUAD	KRTAP10-5 →	+0.014	+4.662	<.001	.005	3	1
LUNG_NSCLC_LUAD	OOSP4B →	+0.017	+5.266	<.001	.001	3	1
SKIN	TEX44 →	+0.032	+4.467	<.001	.004	3	1
SKIN	FAM71C →	+0.015	+4.095	.001	.009	3	1
SKIN	GALP →	+0.017	+4.415	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 11 associations by consensus.

TAAR8 by TIGD6 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →