TIGD5

Across TCGA patient cohorts, TIGD5 protein abundance is significantly associated with the RNA expression of many other genes, with 557 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible TIGD5-associated genes across cancer lineages are MIEF1, PHEX, and NDFIP2. Each is linked with TIGD5 in more than 1 cancer types. Because this analysis shows association rather than direction, both TIGD5-to-partner and partner-to-TIGD5 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TIGD5 versus MIEF1 in BRCA, with a Pearson correlation of -0.93.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TIGD5→partner) and Y-score (partner→TIGD5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	MIEF1 →	-0.473	-0.488	.003	.002	3	1
BRCA	PHEX →	-1.533	-0.513	.009	.005	3	1
BRCA	NDFIP2 →	-1.356	-0.513	.007	.005	3	1
BRCA	PARP4 →	-1.122	-0.414	.006	.006	3	1
BRCA	ZNF200 →	-0.543	-0.513	<.001	.005	3	1
BRCA	BACH2 →	-1.006	-0.513	.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 557 associations by consensus.

TIGD5 vs MIEF1 — BRCA

Explore this scatter interactively →