TIGD5

Across TCGA cell cohorts, TIGD5 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,520 significant associations in total. BONE shows the largest number of these associations.

The most reproducible TIGD5-associated GO terms across cancer lineages are Pre-mRNA catabolic process, Central nervous system morphogenesis, and Negative regulation of translational initiation. Each is linked with TIGD5 in more than 13 cancer types. Because this analysis shows association rather than direction, both TIGD5-to-partner and partner-to-TIGD5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Pre-mRNA catabolic process grouped by TIGD5-low versus TIGD5-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TIGD5→partner) and Y-score (partner→TIGD5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Pre-mRNA catabolic process →	+0.210	+0.899	<.001	<.001	3	14
LUNG_NSCLC_LUSC	Central nervous system morphogenesis →	-0.216	-0.616	<.001	<.001	3	13
BLOOD_Lymphoma	Negative regulation of translational initiation →	+0.081	+0.619	<.001	<.001	3	13
BONE	Transcription pausing by RNA polymerase II →	+0.192	+1.180	<.001	<.001	3	12
LARGE_INTESTINE	Negative regulation of transcription by RNA polymerase III →	+0.154	+0.628	<.001	<.001	3	10
BONE	Regulation of transcription of nucleolar large rRNA by RNA polymerase I →	+0.211	+0.968	<.001	.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,520 associations by consensus.

Pre-mRNA catabolic process by TIGD5 expression — BONE

Explore this box plot interactively →