TIGD2

Across TCGA patient cohorts, TIGD2 RNA expression is significantly associated with the protein abundance of many other proteins, with 12,876 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible TIGD2-associated proteins across cancer lineages are MEF2C_S396, METAP1, and ZEB2_S705. Each is linked with TIGD2 in more than 4 cancer types. Because this analysis shows association rather than direction, both TIGD2-to-partner and partner-to-TIGD2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TIGD2 versus MEF2C_S396 in LSCC, with a Pearson correlation of -0.32.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TIGD2→partner) and Y-score (partner→TIGD2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	MEF2C_S396 →	-0.502	-0.438	.002	.004	3	5
LSCC	METAP1 →	+0.288	+0.374	<.001	.009	3	4
LSCC	ZEB2_S705 →	-0.508	-0.492	<.001	<.001	3	4
UCEC	ARFIP1 →	+0.261	+0.643	<.001	<.001	3	4
OV	MARCKS_S77 →	+1.412	+0.575	<.001	.008	3	3
GBM	MRC2 →	-0.584	-0.421	.001	.002	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,876 associations by consensus.

TIGD2 vs MEF2C_S396 — LSCC

Explore this scatter interactively →