TIGD2

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, TIGD2 protein abundance is significantly associated with the RNA expression of many other genes, with 778 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TIGD2-associated genes across cancer lineages are ZNF385A, CCL17, and ZNF229. Each is linked with TIGD2 in more than 1 cancer types. Because this analysis shows association rather than direction, both TIGD2-to-partner and partner-to-TIGD2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TIGD2 versus ZNF385A in BRCA, with a Pearson correlation of -0.43.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TIGD2→partner) and Y-score (partner→TIGD2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BRCAZNF385A →-1.297-0.441.002.00332
PDACCCL17 →-2.657-0.203<.001.00232
PDACZNF229 →-1.134-0.167.006.00232
BRCAPATZ1 →-0.997-0.687.003<.00131
BRCAMTMR3 →-0.374-0.630.004<.00131
BRCAMSLN →+2.457+0.739.003<.00131
Each partner links to its Q-omics profile. Showing the 6 strongest of 778 associations by consensus.

TIGD2 vs ZNF385A — BRCA

Per-sample scatter of TIGD2 vs ZNF385A in BRCA (Pearson r = -0.43).

Explore this scatter interactively →

Exploration