TICAM2

Across TCGA patient cohorts, TICAM2 RNA expression is significantly associated with the go_rna of many other GO terms, with 7,162 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible TICAM2-associated GO terms across cancer lineages are Vesicle cargo loading, Cellular response to acid chemical, and Regulation of autophagosome assembly. Each is linked with TICAM2 in more than 31 cancer types. Because this analysis shows association rather than direction, both TICAM2-to-partner and partner-to-TICAM2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Vesicle cargo loading grouped by TICAM2-low versus TICAM2-high in DLBC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TICAM2→partner) and Y-score (partner→TICAM2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
DLBC	Vesicle cargo loading →	+0.077	+0.682	<.001	<.001	3	32
SCLC	Cellular response to acid chemical →	+0.094	+0.877	<.001	<.001	3	32
THYM	Regulation of autophagosome assembly →	+0.064	+0.124	<.001	<.001	3	32
SCLC	Vacuole organization →	+0.073	+0.849	<.001	<.001	3	32
SCLC	Response to acid chemical →	+0.087	+0.837	<.001	.001	2	32
DLBC	Negative regulation of macroautophagy →	+0.059	+0.473	<.001	<.001	3	31

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,162 associations by consensus.

Vesicle cargo loading by TICAM2 expression — DLBC

Explore this box plot interactively →