TICAM2

Across TCGA cell cohorts, TICAM2 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,091 significant associations in total. BONE shows the largest number of these associations.

The most reproducible TICAM2-associated GO terms across cancer lineages are Positive regulation of chemokine (C-C motif) ligand 5 production, Regulation of plasminogen activation, and Collagen fibril organization. Each is linked with TICAM2 in more than 17 cancer types. Because this analysis shows association rather than direction, both TICAM2-to-partner and partner-to-TICAM2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of chemokine (C-C motif) ligand 5 production grouped by TICAM2-low versus TICAM2-high in URINARY_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TICAM2→partner) and Y-score (partner→TICAM2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	Positive regulation of chemokine (C-C motif) ligand 5 production →	-0.217	-1.223	.001	<.001	3	18
BONE	Regulation of plasminogen activation →	+0.285	+2.293	<.001	<.001	3	14
BONE	Collagen fibril organization →	+0.345	+2.035	<.001	<.001	3	14
BONE	Negative regulation of plasminogen activation →	+1.150	+2.195	<.001	<.001	3	13
SOFT_TISSUE	Regulation of protein maturation →	+0.163	+1.533	<.001	<.001	3	13
LIVER	PML body organization →	+0.275	+1.874	<.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,091 associations by consensus.

Positive regulation of chemokine (C-C motif) ligand 5 production by TICAM2 expression — URINARY_TRACT

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