TICAM2

Across TCGA cell cohorts, TICAM2 mutation is significantly associated with the RNA expression of many other genes, with 3 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible TICAM2-associated genes across cancer lineages are TAAR8, UBQLN3, and TLE7. Each is linked with TICAM2 in more than 1 cancer types. Because this analysis shows association rather than direction, both TICAM2-to-partner and partner-to-TICAM2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TAAR8 grouped by TICAM2-low versus TICAM2-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TICAM2→partner) and Y-score (partner→TICAM2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	TAAR8 →	+0.011	+4.384	<.001	.006	3	1
BLOOD_Leukemia	UBQLN3 →	+0.039	+3.551	<.001	.009	3	1
BLOOD_Leukemia	TLE7 →	+0.027	+4.384	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

TAAR8 by TICAM2 expression — BLOOD_Leukemia

Explore this box plot interactively →