TICAM1

Across TCGA cell cohorts, TICAM1 mutation is significantly associated with the RNA expression of many other genes, with 168 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible TICAM1-associated genes across cancer lineages are FAM24A, ADAM2, and ZIM3. Each is linked with TICAM1 in more than 1 cancer types. Because this analysis shows association rather than direction, both TICAM1-to-partner and partner-to-TICAM1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, FAM24A grouped by TICAM1-low versus TICAM1-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TICAM1→partner) and Y-score (partner→TICAM1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	FAM24A →	+0.073	+6.247	<.001	<.001	3	2
CNS	ADAM2 →	+0.027	+4.169	<.001	.008	3	2
BLOOD_Lymphoma	ZIM3 →	+0.006	+6.247	<.001	<.001	3	1
BLOOD_Lymphoma	WFDC8 →	+0.022	+4.867	<.001	.009	3	1
BLOOD_Lymphoma	ADIPOQ →	+0.013	+5.209	<.001	.005	3	1
BLOOD_Lymphoma	OR7A5 →	+0.026	+5.643	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 168 associations by consensus.

FAM24A by TICAM1 expression — BLOOD_Lymphoma

Explore this box plot interactively →