TIAM2

Across TCGA patient cohorts, TIAM2 RNA expression is significantly associated with the protein abundance of many other proteins, with 14,446 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible TIAM2-associated proteins across cancer lineages are SNX9, ISLR, and PRRX1. Each is linked with TIAM2 in more than 5 cancer types. Because this analysis shows association rather than direction, both TIAM2-to-partner and partner-to-TIAM2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TIAM2 versus SNX9 in OV, with a Pearson correlation of 0.38.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TIAM2→partner) and Y-score (partner→TIAM2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	SNX9 →	+0.256	+0.391	.004	.002	3	6
PDAC	ISLR →	+0.771	+0.436	<.001	<.001	3	6
OV	PRRX1 →	+0.642	+0.426	<.001	.006	3	6
HNSC	PCOLCE →	+0.768	+0.605	<.001	<.001	3	5
OV	THBS2 →	+1.149	+0.448	.001	.002	3	5
HNSC	DBN1 →	+0.385	+0.688	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,446 associations by consensus.

TIAM2 vs SNX9 — OV

Explore this scatter interactively →