TIAM2

Across TCGA patient cohorts, TIAM2 protein abundance is significantly associated with the RNA expression of many other genes, with 3,721 significant associations in total. GBM shows the largest number of these associations.

The most reproducible TIAM2-associated genes across cancer lineages are ADAMTSL2, CSMD3, and IFNA2. Each is linked with TIAM2 in more than 1 cancer types. Because this analysis shows association rather than direction, both TIAM2-to-partner and partner-to-TIAM2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TIAM2 versus ADAMTSL2 in OV, with a Pearson correlation of 0.83.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TIAM2→partner) and Y-score (partner→TIAM2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	ADAMTSL2 →	+1.230	+0.505	.002	.008	3	2
GBM	CSMD3 →	+0.988	+0.666	<.001	<.001	3	2
GBM	IFNA2 →	+0.463	+0.751	<.001	<.001	3	2
GBM	TUBB8P9 →	+0.127	+0.480	<.001	.002	3	2
OV	HELQ →	+0.304	+0.505	.009	.008	3	1
OV	MFSD2A →	+2.965	+0.505	.009	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,721 associations by consensus.

TIAM2 vs ADAMTSL2 — OV

Explore this scatter interactively →