TIAM2

Across TCGA cell cohorts, TIAM2 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,062 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible TIAM2-associated GO terms across cancer lineages are Regulation of DNA-templated transcription initiation, Termination of RNA polymerase II transcription, and Protein-DNA complex assembly. Each is linked with TIAM2 in more than 13 cancer types. Because this analysis shows association rather than direction, both TIAM2-to-partner and partner-to-TIAM2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of DNA-templated transcription initiation grouped by TIAM2-low versus TIAM2-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TIAM2→partner) and Y-score (partner→TIAM2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Regulation of DNA-templated transcription initiation →	+0.067	+1.498	<.001	<.001	3	14
OVARY	Termination of RNA polymerase II transcription →	+0.120	+1.053	<.001	<.001	3	13
LUNG_NSCLC_LUSC	Protein-DNA complex assembly →	+0.066	+1.481	<.001	.002	2	14
STOMACH	Positive regulation of DNA-templated transcription, elongation →	+0.098	+1.767	<.001	<.001	3	12
STOMACH	Positive regulation of transcription initiation by RNA polymerase II →	+0.070	+1.534	<.001	<.001	3	12
URINARY_TRACT	Transcription initiation at RNA polymerase II promoter →	+0.064	+0.903	<.001	.008	2	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,062 associations by consensus.

Regulation of DNA-templated transcription initiation by TIAM2 expression — STOMACH

Explore this box plot interactively →