Across TCGA pan-cancer cohorts, TIAF1 Mutation is linked to patient survival in 2 of 34 cancer types, making it a survival-associated TIAF1 data layer compared with 25 for mass-spec protein.

The strongest signal is observed in prostate adenocarcinoma (PRAD), where higher TIAF1 Mutation is associated with worse disease-free survival. In most high-consensus cancer types, elevated TIAF1 expression acts as an unfavorable survival marker.

PRAD and KIRP are the cancer types where TIAF1 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
PRAD	DFS	Median	All	0.085	0.774	<.001	6	view →
KIRP	OS	Median	All	0.248	0.705	.049	2	view →

Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

Exploration

Same gene, other analysis: TIAF1 tumor-vs-normal RNA expression · all TIAF1 data types