Across TCGA patient cohorts, TIAF1 mutation is significantly associated with the RNA expression of many other genes, with 388 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TIAF1-associated genes across cancer lineages are NCAPD3, GUF1, and OBI1. Each is linked with TIAF1 in more than 1 cancer types. Because this analysis shows association rather than direction, both TIAF1-to-partner and partner-to-TIAF1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TIAF1→partner) and Y-score (partner→TIAF1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	NCAPD3 →	+0.809	+3.470	.001	.003	3	1
UCEC	GUF1 →	+0.625	+3.346	<.001	.005	3	1
UCEC	OBI1 →	+0.554	+3.459	.009	.005	3	1
UCEC	FARP1 →	+0.614	+3.470	.005	.003	3	1
UCEC	HEATR3 →	+0.776	+3.470	<.001	.003	3	1
UCEC	RNF166 →	+0.522	+3.210	.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 388 associations by consensus.

Exploration

TIAF1 survival (RNA) · tumor vs normal (RNA) · all TIAF1 data types