Across TCGA patient cohorts, TIAF1 mutation is significantly associated with the total protein of many other genes, with 15 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TIAF1-associated genes across cancer lineages are FOXO3a, INPP4B, and Ku80. Each is linked with TIAF1 in more than 1 cancer types. Because this analysis shows association rather than direction, both TIAF1-to-partner and partner-to-TIAF1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TIAF1→partner) and Y-score (partner→TIAF1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	FOXO3a →	+0.111	+2.183	.036	.035	3	1
UCEC	INPP4B →	-0.363	-3.169	.032	.019	3	1
UCEC	Ku80 →	+0.409	+3.335	<.001	.005	3	1
UCEC	MEK1 →	+0.474	+3.169	.013	.019	3	1
UCEC	PI3K-p85 →	+0.231	+2.817	.035	.036	3	1
UCEC	Tuberin →	+0.588	+3.331	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 15 associations by consensus.

Exploration

TIAF1 survival (RNA) · tumor vs normal (RNA) · all TIAF1 data types