THYN1

Across TCGA pan-cancer cohorts, THYN1 mass-spec protein is linked to patient survival in 7 of 34 cancer types, making it a survival-associated THYN1 data layer compared with 25 for mass-spec protein and 4 for mutation status.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher THYN1 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated THYN1 expression acts as an unfavorable survival marker, although some lineages such as COAD and LUAD show a favorable association.

COAD, UCEC, and LUAD are the cancer types where THYN1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	DFS	Median	All	1.000	0.922	.017	30	view →
UCEC	OS	Median	II,III,IV	0.647	1.000	.017	12	view →
LUAD	OS	Tertile	II,III,IV	1.000	0.320	.007	11	view →
PDAC	DFS	Median	All	0.860	0.670	.022	6	view →
GBM	OS	Tertile	All	0.704	0.459	.042	2	view →
LSCC	DFS	Median	II,III,IV	1.000	0.571	.030	2	view →
HNSC	OS	Median	III,IV	0.801	0.898	.044	1	view →

Pink = unfavorable, green = favorable. Showing the 7 strongest of 7 lineages.

THYN1–COAD (DFS)

Open the COAD breakdown →