THRB

Across TCGA patient cohorts, THRB protein abundance is significantly associated with the RNA expression of many other genes, with 191 significant associations in total. GBM shows the largest number of these associations.

The most reproducible THRB-associated genes across cancer lineages are AHR, ITK, and KAT2B. Each is linked with THRB in more than 1 cancer types. Because this analysis shows association rather than direction, both THRB-to-partner and partner-to-THRB results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, THRB versus AHR in GBM, with a Pearson correlation of -0.63.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (THRB→partner) and Y-score (partner→THRB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	AHR →	-1.426	-0.583	.002	<.001	3	1
GBM	ITK →	-1.237	-0.503	.004	.007	3	1
GBM	KAT2B →	+0.659	+0.403	.001	.002	3	1
GBM	ITGA4 →	-1.147	-0.373	.001	.005	3	1
GBM	ICMT →	-0.463	-0.474	.009	.008	3	1
GBM	CA14 →	+1.052	+0.466	.002	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 191 associations by consensus.

THRB vs AHR — GBM

Explore this scatter interactively →