Across TCGA pan-cancer cohorts, THRAP3P2 RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of THRAP3P2’s most consistent transcriptional readouts.
The strongest signal is observed in kidney chromophobe (KICH), where THRAP3P2 RNA is repressed in tumor relative to normal tissue. In most cancer types THRAP3P2 is over-expressed in tumor, although a few such as KICH show the opposite, repressed pattern.
KICH and COAD are the cancer types where THRAP3P2 tumor–normal differential expression is most reproducible.