THRAP3

Across TCGA patient cohorts, THRAP3 RNA expression is significantly associated with the protein abundance of many other proteins, with 12,826 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible THRAP3-associated proteins across cancer lineages are SPCS3, ERH, and YTHDF2. Each is linked with THRAP3 in more than 4 cancer types. Because this analysis shows association rather than direction, both THRAP3-to-partner and partner-to-THRAP3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, THRAP3 versus SPCS3 in LSCC, with a Pearson correlation of -0.43.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (THRAP3→partner) and Y-score (partner→THRAP3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	SPCS3 →	-0.529	-0.288	<.001	.002	3	5
PDAC	ERH →	+0.384	+0.334	.001	<.001	3	5
GBM	YTHDF2 →	+0.428	+0.344	<.001	<.001	3	5
LSCC	SEC11C →	-0.832	-0.324	.002	.001	3	5
PDAC	PRC1_T481 →	+1.005	+0.348	.002	.004	3	4
GBM	ZMYM4 →	+0.444	+0.296	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,826 associations by consensus.

THRAP3 vs SPCS3 — LSCC

Explore this scatter interactively →