THRAP3

Across TCGA patient cohorts, THRAP3 protein abundance is significantly associated with the RNA expression of many other genes, with 14,662 significant associations in total. GBM shows the largest number of these associations.

The most reproducible THRAP3-associated genes across cancer lineages are SASS6, PASK, and RBBP4. Each is linked with THRAP3 in more than 6 cancer types. Because this analysis shows association rather than direction, both THRAP3-to-partner and partner-to-THRAP3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, THRAP3 versus SASS6 in LSCC, with a Pearson correlation of 0.53.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (THRAP3→partner) and Y-score (partner→THRAP3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	SASS6 →	+0.800	+0.259	<.001	<.001	3	7
HNSC	PASK →	+0.453	+0.128	<.001	<.001	3	7
LSCC	RBBP4 →	+0.603	+0.244	<.001	<.001	3	7
LSCC	C17orf80 →	+0.505	+0.248	<.001	<.001	3	6
LSCC	MIS18A →	+0.654	+0.168	<.001	<.001	3	6
OV	PTH1R →	-1.066	-0.276	.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,662 associations by consensus.

THRAP3 vs SASS6 — LSCC

Explore this scatter interactively →