THRAP3

Across TCGA cell cohorts, THRAP3 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,490 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible THRAP3-associated GO terms across cancer lineages are Negative regulation of cell cycle process, Regulation of G2/M transition of mitotic cell cycle, and Mitotic nuclear division. Each is linked with THRAP3 in more than 17 cancer types. Because this analysis shows association rather than direction, both THRAP3-to-partner and partner-to-THRAP3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of cell cycle process grouped by THRAP3-low versus THRAP3-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (THRAP3→partner) and Y-score (partner→THRAP3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Negative regulation of cell cycle process →	+0.068	+0.994	<.001	<.001	3	18
UPPER_AERODIGESTIVE_TRACT	Regulation of G2/M transition of mitotic cell cycle →	+0.065	+0.551	<.001	<.001	3	17
SOFT_TISSUE	Mitotic nuclear division →	+0.110	+0.973	<.001	<.001	3	17
SOFT_TISSUE	Centrosome duplication →	+0.122	+1.007	<.001	<.001	3	17
PANCREAS	Regulation of chromosome condensation →	+0.154	+0.671	<.001	.004	3	17
BONE	DNA replication →	+0.093	+0.403	<.001	.005	3	17

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,490 associations by consensus.

Negative regulation of cell cycle process by THRAP3 expression — SOFT_TISSUE

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